• Agnoprotein of polyomavirus BK interacts With proliferating cell nuclear antigen and inhibits DNA replication 

      Gerits, Nancy; Johannessen, Mona; Tümmler, Conny; Walquist, Mari; Kostenko, Sergiy; Snapkov, Igor; van Loon, Barbara; Ferrari, Elena; Hübscher, Ulrich; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-01)
      Background: The human polyomavirus BK expresses a 66 amino-acid peptide referred to as agnoprotein. Though mutants lacking agnoprotein are severely reduced in producing infectious virions, the exact function of this peptide remains incompletely understood. To elucidate the function of agnoprotein, we searched for novel cellular interaction partners. <p>Methods: Yeast-two hybrid assay was performed ...
    • Antioxidant and Anti-Inflammatory Activities in Extracts from Minke Whale (Balaenoptera acutorostrata) Blubber 

      Walquist, Mari; Stormo, Svein Kristian; Jensen, Ida-Johanne; Østerud, Bjarne; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-08)
      Intake of long-chain omega-3 polyunsaturated fatty acids (LC-n3-PUFA) is commonly recognized to reduce cardiovascular disease (CVD). In previous studies, cold-pressed whale oil (CWO) and cod liver oil (CLO) were given as a dietary supplement to healthy volunteers. Even though CWO contains less than half the amount of LC-n3-PUFA of CLO, CWO supplement resulted in beneficial effects on anti-inflammatory ...
    • BKV Agnoprotein Interacts with alpha-Soluble N-Ethylmaleimide-Sensitive Fusion Attachment Protein, and Negatively Influences Transport of VSVG-EGFP 

      Johannessen, Mona; Walquist, Mari; Gerits, Nancy; Dragset, Marte Singsås; Spang, Anne; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The human polyomavirus BK (BKV) infects humans worldwide and establishes a persistent infection in the kidney. The BK virus genome encodes three regulatory proteins, large and small tumor-antigen and the agnoprotein, as well as the capsid proteins VP1 to VP3. Agnoprotein is conserved among BKV, JC virus (JCV) and SV40, and agnoprotein-deficient mutants reveal reduced viral propagation. Studies with ...
    • Cold-pressed minke whale oil reduces circulating LDL/VLDL-cholesterol, lipid oxidation and atherogenesis in apolipoprotein E-deficient mice fed a Western-type diet for 13 weeks 

      Walquist, Mari; Stormo, Svein Kristian; Østerud, Bjarne; Elvevoll, Edel Oddny; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-04)
      Background<br> Long-chain n3-polyunsaturated fatty acids (LC n3-PUFA) are well known for their anti-inflammatory activity and their impact on cardiovascular disease. Cold-pressed whale oil (CWO) has half the amount of LC n3-PUFA compared to cod liver oil (CLO). Still, there has been observed more pronounced beneficial effects on cardiovascular disease markers from intake of CWO compared to intake ...
    • Dietary intake of cod and scallop reduces atherosclerotic burden in female apolipoprotein E-deficient mice fed a Western-type high fat diet for 13 weeks 

      Jensen, Ida-Johanne; Walquist, Mari; Liaset, Bjørn; Elvevoll, Edel Oddny; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-02)
      <b>Background:</b> It is now increasingly recognized that the beneficial effects of seafood consumption is not limited to lipids and fatty acid, but that the protein part, i.e., peptides and amino acids, together with vitamins and even unknown bioactive constituents also are important for disease prevention. This study was designed to evaluate the putative anti-atherogenic effects of different ...
    • Differentially Expressed MicroRNAs in Meningiomas Grades I and II Suggest Shared Biomarkers with Malignant Tumors 

      El-Gewely, Mohamed Raafat; Andreassen, Morten; Walquist, Mari; Ursvik, Anita; Knutsen, Erik; Nystad, Mona; Coucheron, Dag H; Myrmel, Kristin Smistad; Hennig, Rune; Johansen, Steinar D (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-03)
      Meningiomas represent the most common primary tumors of the central nervous system, but few microRNA (miRNA) profiling studies have been reported so far. Deep sequencing of small RNA libraries generated from two human meningioma biopsies WHO grades I (benign) and II (atypical) were compared to excess dura controls. Nineteen differentially expressed miRNAs were validated by RT-qPCR using tumor RNA ...